Carbohydrate-active enzymes from pigmented Bacilli: a genomic approach to assess carbohydrate utilization and degradation
2011
Carbohydrate-active enzymes from pigmented Bacilli
publication
Evidence: moderate
Author Information
Author(s): Manzo Nicola, D'Apuzzo Enrica, Coutinho Pedro M, Cutting Simon M, Henrissat Bernard, Ricca Ezio
Primary Institution: Federico II University of Naples
Hypothesis
The gut is the real habitat of spore-formers.
Conclusion
The two pigmented Bacilli are adapted to the intestinal environment and are suited to grow and colonize the human gut.
Supporting Evidence
- B. firmus and B. indicus genomes contain high numbers of carbohydrate-active enzymes.
- Both Bacilli can degrade and utilize various carbohydrates as their sole carbon source.
- Carotenoid production is repressed by the presence of certain carbohydrates.
- B. indicus HU36 produces a levan-based biofilm.
- B. indicus HU36 is more efficient than Lactobacillus rhamnosus GG in binding and degrading mucin.
Takeaway
Scientists studied two types of bacteria that can make colors and found they can eat different sugars and live in our intestines.
Methodology
The study involved genomic analysis and experimental validation of carbohydrate-active enzymes in two pigmented Bacilli.
Digital Object Identifier (DOI)
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