Tracking Vibrio cholerae O139 in Calcutta (1992-1998)
Author Information
Author(s): Arnab Basu, Pallavi Garg, Simanti Datta, Soumen Chakraborty, Tanuja Bhattacharya, Asis Khan, T. Ramamurthy, S.K. Bhattacharya, Shinji Yamasaki, Yoshifumi Takeda, G. Balakrish Nair
Primary Institution: National Institute of Cholera and Enteric Diseases, Calcutta, India
Hypothesis
The study aims to track and catalog changes in Vibrio cholerae O139 strains in Calcutta from 1992 to 1998.
Conclusion
The study found that Vibrio cholerae O139 was the dominant cholera-causing serogroup during certain periods, with significant changes in antibiotic resistance patterns over time.
Supporting Evidence
- V. cholerae O139 was first identified in 1992 and became the dominant serogroup in Calcutta during specific years.
- Antibiotic resistance patterns showed significant changes, with some strains becoming sensitive to previously resistant antibiotics.
- Molecular studies indicated continuous emergence of new epidemic clones of V. cholerae O139.
Takeaway
This study looked at how a germ called Vibrio cholerae O139 changed over several years in Calcutta, especially how it got stronger against medicines.
Methodology
The study involved hospital surveillance and bacteriological examination of stool samples from cholera patients in Calcutta.
Limitations
The study is limited to data from Calcutta and may not represent trends in other regions.
Participant Demographics
Patients admitted to the Infectious Diseases Hospital in Calcutta with diarrhea or dysentery.
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