A multi-nutrient supplement reduced markers of inflammation and improved physical performance in active individuals of middle to older age: a randomized, double-blind, placebo-controlled study
2011

Multi-nutrient Supplement Improves Inflammation and Performance in Middle-Aged Individuals

Sample size: 31 publication 10 minutes Evidence: moderate

Author Information

Author(s): Courtenay Dunn-Lewis, William J Kraemer, Brian R Kupchak, Neil A Kelly, Brent A Creighton, Hui-Ying Luk, Kevin D Ballard, Brett A Comstock, Tunde K Szivak, David R Hooper, Craig R Denegar, Jeff S Volek

Primary Institution: University of Connecticut

Hypothesis

Does a multi-nutrient supplement containing branched chain amino acids, taurine, anti-inflammatory plant extracts, and B vitamins improve inflammatory status and physical performance in middle-aged individuals?

Conclusion

A multi-nutrient supplement effectively reduces inflammation and improves physical performance in middle-aged individuals.

Supporting Evidence

  • IL-6 levels decreased significantly in both men and women after supplementation.
  • Men showed improved vertical jump power and grip strength after taking the supplement.
  • Women reported decreased anxiety and improved balance after supplementation.

Takeaway

Taking a special mix of nutrients can help older people feel better and perform better in physical activities.

Methodology

The study used a randomized, double-blind, placebo-controlled, cross-over design with 31 healthy, active participants who underwent two 28-day supplementation cycles.

Potential Biases

Potential bias due to funding from the supplement manufacturer.

Limitations

The study was limited to healthy, recreationally active individuals and may not apply to those with pre-existing conditions.

Participant Demographics

31 healthy and active individuals (16 men, 15 women) aged 40-70 years.

Statistical Information

P-Value

p ≤ 0.05

Statistical Significance

p ≤ 0.05

Digital Object Identifier (DOI)

10.1186/1475-2891-10-90

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