Biochemical and Molecular Aspects of Vascular Adrenergic Regulation of Blood Pressure in the Elderly
2012
Understanding Blood Pressure Regulation in the Elderly
publication
Evidence: moderate
Author Information
Author(s): W. E. Schutzer, S. L. Mader
Primary Institution: Portland VA Medical Center and Research Service—RD 26, Oregon Health and Science University School of Medicine
Hypothesis
The study investigates the age-related decline in vascular beta-adrenergic receptor-mediated function and its impact on blood pressure regulation.
Conclusion
The study concludes that aging leads to impaired beta-adrenergic receptor signaling, which may contribute to various cardiovascular disorders in the elderly.
Supporting Evidence
- Aging is a primary independent risk factor for cardiovascular disorders.
- Beta-adrenergic receptors are important regulators of cardiovascular physiology.
- Age-related changes in beta-adrenergic receptor signaling can lead to hypertension and other cardiovascular issues.
Takeaway
As people get older, their bodies don't respond as well to certain signals that help control blood pressure, which can lead to health problems.
Digital Object Identifier (DOI)
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