Lumbar disc herniation in three patients with cystic fibrosis: a case series
2011

Lumbar Disc Herniation in Cystic Fibrosis Patients

Sample size: 3 publication Evidence: low

Author Information

Author(s): Denne Christian, Vogl-Voswinckel Anna E, Wurmser Harald, Steinborn Marc, Spaeth Manfred, Gruebl Armin, Burdach Stefan

Primary Institution: Department of Pediatrics, Kinderklinik München Schwabing, Klinikum Schwabing StKM GmbH and Klinikum Rechts der Isar (AöR) of the Technical University (TU) München, Munich, Germany

Hypothesis

The prevalence of lumbar disc herniation (LDH) in cystic fibrosis (CF) patients may be higher than previously reported.

Conclusion

Lumbar disc herniation can lead to a vicious cycle for patients with cystic fibrosis as it may promote pulmonary infections.

Supporting Evidence

  • The point prevalence of LDH was 6.5% in the CF clinic.
  • Two of the three patients had a positive family history for LDH.
  • Patient 3 died due to complications related to her lung function and LDH.

Takeaway

Some people with cystic fibrosis can have back problems like disc herniation, which can make their breathing worse and lead to more health issues.

Methodology

Case series of three patients with cystic fibrosis who experienced lumbar disc herniation.

Limitations

The study is based on a small sample size and may not represent the broader CF population.

Participant Demographics

Three Caucasian patients aged 21 to 23 years with cystic fibrosis.

Digital Object Identifier (DOI)

10.1186/1752-1947-5-440

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