Risk Factors for Lymph Node Metastasis in Papillary Thyroid Cancer
Author Information
Author(s): Sudhi Agarwal, Gyan Chand, Sushila Jaiswal, Anjali Mishra, Gaurav Agarwal, Amit Agarwal, A. K. Verma, S. K. Mishra
Primary Institution: Sanjay Gandhi Postgraduate Institute of Medical Sciences
Hypothesis
What are the patterns and risk factors for central compartment lymph node metastasis in papillary thyroid cancer?
Conclusion
Tumor size is a significant risk factor for central compartment lymph node metastasis in papillary thyroid cancer.
Supporting Evidence
- 59.6% of patients had central compartment lymph node metastasis.
- 60.72% of those with metastasis had bilateral involvement.
- Multicentricity and ipsilateral lymph node metastasis were significant predictors for contralateral metastasis.
Takeaway
This study looked at patients with thyroid cancer and found that bigger tumors are more likely to spread to nearby lymph nodes.
Methodology
A prospective study of 47 patients with papillary thyroid cancer who underwent total thyroidectomy with central compartment dissection.
Potential Biases
Nonrandomized nature of the study may introduce bias.
Limitations
The study has a small sample size and shorter follow-ups.
Participant Demographics
Mean age was 35.79 years, with a female to male ratio of 31:16.
Statistical Information
P-Value
P=0.018 for tumor size and CCM.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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