Effects of Preoperative Feeding with Whey Protein and Carbohydrates
Author Information
Author(s): Francine Perrone, Antônio C. da-Silva-Filho, Isa F. Adôrno, Nadia T. Anabuki, Fernando S. Leal, Tariane Colombo, Benedito D. da Silva, Diana B. Dock-Nascimento, Aderson Damião, José E. de Aguilar-Nascimento
Primary Institution: Julio Muller University Hospital, Federal University of Mato Grosso, Brazil
Hypothesis
The addition of whey protein to a carbohydrate-based drink reduces the inflammatory response and insulin resistance.
Conclusion
Shortening the pre-operative fasting using carbohydrates and whey protein is safe and reduces insulin resistance and postoperative acute phase response in elective moderate operations.
Supporting Evidence
- Post-operative insulin resistance was lower in the CHO-P group compared to the CO group.
- The CHO-P group showed a decrease in CRP elevation and CRP/albumin ratio.
- A greater proportion of patients in the CHO-P group had a normal CRP/albumin ratio compared to the CO group.
Takeaway
Giving patients a drink with carbohydrates and whey protein before surgery helps them recover better and feel less insulin resistance.
Methodology
Seventeen patients were randomized to receive either a carbohydrate and whey protein drink or water before surgery, with blood samples taken for analysis.
Potential Biases
Potential bias due to the small number of cases and the lack of a group receiving only whey protein.
Limitations
The small sample size may limit the generalizability of the findings.
Participant Demographics
Adults aged 18-65, both sexes, scheduled for elective moderate operations.
Statistical Information
P-Value
0.03
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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