COMBINED MULTIMODAL EXERCISE AND COGNITIVE TRAINING FOR PERSONS WITH MILD DEMENTIA: A RANDOMIZED CONTROLLED TRIAL
2024

Exercise and Cognitive Training for Mild Dementia

Sample size: 72 publication Evidence: moderate

Author Information

Author(s): Xue Dandan, Li Polly Wai Chi, Yu Doris Sau Fung

Primary Institution: The University of Hong Kong

Hypothesis

The effects of combined exercise and cognitive interventions among persons with mild dementia are not known.

Conclusion

The combined multimodal exercise and cognitive training was effective in improving cognition and reducing neuropsychic symptoms among persons with mild dementia.

Supporting Evidence

  • The intervention group showed significantly greater improvement in global cognition.
  • Immediate recall improved significantly in the intervention group.
  • Short-term delayed recall showed significant improvement.
  • Long-term delayed recall improved significantly.
  • Cued recall showed significant improvement.
  • Word recognition improved significantly.
  • The intervention group demonstrated a significant reduction in the severity of neuropsychic symptoms.

Takeaway

People with mild dementia can get better at thinking and feel less confused when they do exercise and brain games together.

Methodology

This study was a randomized controlled trial comparing a caregiver-assisted combined multimodal exercise and cognitive training intervention to health education.

Limitations

No significant changes were observed in several cognitive and functional measures, indicating potential limitations in the intervention's effectiveness.

Participant Demographics

Participants were persons with mild dementia.

Statistical Information

P-Value

p < 0.001

Confidence Interval

[1.254, 3.681]

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1093/geroni/igae098.2265

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