Characterization of an Outbreak of Hand, Foot, and Mouth Disease in Nanchang, China in 2010
2011

Outbreak of Hand, Foot, and Mouth Disease in Nanchang, China

Sample size: 109 publication Evidence: moderate

Author Information

Author(s): Liu Michelle Y., Liu Weiyong, Luo Jun, Liu Yingle, Zhu Yang, Berman Hillary, Wu Jianguo

Primary Institution: State Key Laboratory of Virology, College of Life Sciences, Wuhan University

Hypothesis

What are the epidemiological characteristics of the HFMD and EV71 outbreak in Nanchang, China in 2010?

Conclusion

The study found that over 90% of HFMD cases were in children under 8 years old, with EV71 being the most common virus detected.

Supporting Evidence

  • 109 HFMD cases were reported and analyzed during the outbreak.
  • Children aged younger than 8 years represented more than 90% of the reported cases.
  • Laboratory studies detected a high prevalence of EV71 among the cases.

Takeaway

In Nanchang, many kids got sick with hand, foot, and mouth disease, mostly those younger than 8, and a virus called EV71 was found in most cases.

Methodology

The study involved epidemiological and laboratory analyses of HFMD cases reported at a hospital in Nanchang, including PCR testing for enteroviruses.

Potential Biases

Data collection may have been artificial and partial, leading to potential false positives or negatives in laboratory results.

Limitations

The study may not fully represent the transmission patterns due to potential biases in data collection and laboratory testing.

Participant Demographics

The majority of cases were in children aged 8 years or younger, with a mean age of 4.37 years.

Digital Object Identifier (DOI)

10.1371/journal.pone.0025287

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