Headache and migraine during pregnancy and puerperium: the MIGRA-study
2011

Headaches and Migraines During Pregnancy

Sample size: 2126 publication Evidence: moderate

Author Information

Author(s): Kvisvik Elisabeth Volden, Stovner Lars Jacob, Helde Grethe, Bovim Gunnar, Linde Mattias

Primary Institution: Norwegian University of Science and Technology

Hypothesis

What is the course of headaches and migraines during pregnancy and postpartum?

Conclusion

Most women with migraines experience a decrease in headache frequency during pregnancy, but there is an increase in intensity and duration postpartum.

Supporting Evidence

  • 208 women with migraine filled in detailed headache diaries during pregnancy.
  • Freedom from earlier headaches during pregnancy was significantly more common than new onset of headache.
  • There was a gradual decrease in headache frequency during pregnancy.
  • Postpartum, there was a significant increase in headache intensity and duration.

Takeaway

Many women who usually get headaches feel better when they are pregnant, but they might have more headaches after the baby is born.

Methodology

The study involved questionnaires and headache diaries filled out by pregnant women to track headache occurrences and characteristics.

Potential Biases

Self-assessment of migraine may lead to underreporting or misclassification of headache types.

Limitations

Two-thirds of participants had incomplete diary entries, which may affect the results.

Participant Demographics

Mean age of participants was 28.4 years, with a mix of nulliparous and multiparous women.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1007/s10194-011-0329-1

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