Benefits of ICU Admission in Critically Ill Patients
Author Information
Author(s): Romain Pirracchio, Charles Sprung, Didier Payen, Sylvie Chevret
Primary Institution: Hôpital Saint Louis, APHP; Université Paris 7 Diderot
Hypothesis
Does ICU admission reduce hospital mortality in critically ill patients?
Conclusion
The study found no significant beneficial effect of ICU admission on hospital mortality.
Supporting Evidence
- The study included 8,201 patients, with 6,752 admitted to the ICU.
- Instrumental variable methods were used to assess the impact of ICU admission.
- The analysis showed increased hospital mortality associated with ICU admission after adjusting for confounders.
Takeaway
The study looked at whether going to the ICU helps sick patients live longer, but it found that it might not make a difference.
Methodology
The study used a cohort of patients and compared ICU admission effects using instrumental variables, standard regression, and propensity score matched analyses.
Potential Biases
There is a risk of selection bias due to nonrandomized designs.
Limitations
The study faced limitations related to unmeasured confounding and the statistical power of the methods used.
Participant Demographics
The cohort included adult patients evaluated for ICU admission across seven European countries.
Statistical Information
P-Value
0.005
Confidence Interval
1.07-1.46
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website