HIV-1 Virological Synapse: Live Imaging of Transmission
2010
HIV-1 Virological Synapse: Live Imaging of Transmission
publication
Evidence: high
Author Information
Author(s): Feldmann Jerome, Schwartz Olivier
Primary Institution: Institut Pasteur
Conclusion
Live imaging has shown that HIV-1 uses a highly efficient method to spread between cells through the virological synapse.
Supporting Evidence
- HIV-1 can infect cells through direct contacts across a specialized structure called the virological synapse.
- Live imaging has revealed that the virus can transfer efficiently between cells using various mechanisms.
- Different modes of HIV-1 transfer have been visualized, including through filopodia and nanotubes.
Takeaway
HIV-1 can jump from one infected cell to another without going into the air, using special connections called virological synapses.
Methodology
The study utilized live cell imaging techniques to visualize HIV-1 transfer between cells.
Digital Object Identifier (DOI)
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