Mind the Gap: How Some Viruses Infect Their Hosts
2010
Understanding How Some Viruses Infect Their Hosts
Commentary
Evidence: moderate
Author Information
Author(s): Peter E. Prevelige Jr.
Primary Institution: University of Alabama at Birmingham
Hypothesis
What are the molecular mechanics of the infection process of phages?
Conclusion
The study provides unique molecular insights into how the DNA of the phage P-SSP7 translocates into its host during infection.
Supporting Evidence
- The study reveals how the P-SSP7 phage infects Prochlorococcus marinus, a common ocean microorganism.
- Using advanced imaging techniques, the researchers captured the process of DNA translocation from the phage to the host.
- The findings suggest that the structural changes in the phage are crucial for understanding viral infections.
Takeaway
This study looks at how a virus injects its DNA into a tiny ocean organism, helping us understand how viruses work.
Methodology
The study used cryo-electron microscopy and cryo-electron tomography to analyze the structural changes during the infection process.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website