Fluvoxamine for Menopausal Symptoms in Japanese Women
Author Information
Author(s): Oishi Akira, Mochizuki Yoshiko, Otsu Reiko, Inaba Noriyuki
Primary Institution: Dokkyo University School of Medicine
Hypothesis
Is fluvoxamine effective in treating climacteric symptoms in Japanese women?
Conclusion
Fluvoxamine was effective in treating depressive moods and associated vasomotor symptoms in climacteric women.
Supporting Evidence
- Fluvoxamine significantly decreased depressive symptoms after 2 and 6 weeks.
- Mean SMI scores declined significantly after 6 weeks of treatment.
- Four participants discontinued fluvoxamine due to adverse effects.
Takeaway
This study tested a medicine called fluvoxamine to help women going through menopause feel better. It worked for some symptoms like feeling sad and hot flashes.
Methodology
Twenty-two patients were given fluvoxamine (50 mg daily) and assessed for symptoms at baseline, 2 weeks, and 6 weeks.
Potential Biases
Potential bias due to the small sample size and lack of control group.
Limitations
The study had an uncontrolled design and a small sample size.
Participant Demographics
Mean age of participants was 52.9 years, with 8 perimenopausal and 14 postmenopausal women.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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