Diagnosis/Classification Criteria for Behcet's Disease
2012
Comparing Diagnosis Criteria for Behcet's Disease
Sample size: 2556
publication
Evidence: high
Author Information
Author(s): Fereydoun Davatchi
Primary Institution: Tehran University of Medical Sciences
Hypothesis
The study aims to compare the performance of the International Study Group (ISG) criteria and the International Criteria for Behcet's Disease (ICBD).
Conclusion
ICBD has better sensitivity and accuracy than ISG.
Supporting Evidence
- The sensitivity for ISG was 65.4%, 78.1%, 83.7% and for ICBD 87%, 98.2%, and 96.5%.
- The specificity for ISG was 99.2%, 98.8%, 89.5% and for ICBD 94.1%, 95.6%, and 73.7%.
- The accuracy for ISG was 74.2%, 85.5%, 85.5% and for ICBD 88.9%, 97.3%, and 89.5%.
Takeaway
This study looked at two ways to diagnose a disease called Behcet's Disease and found that one way is better at finding people who have it.
Methodology
The performance of ISG and ICBD criteria was tested in three independent cohorts of patients from China, Iran, and Germany.
Participant Demographics
Patients from Far-East (China), Middle-East (Iran), and Europe (Germany).
Statistical Information
P-Value
<0.001
Confidence Interval
95% CI 95.3–96.8
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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