Mapping Genetic Traits for T Cells in Pigs
Author Information
Author(s): Lu Xin, Liu Jian-Feng, Gong Yuan-Fang, Wang Zhi-Peng, Liu Yang, Zhang Qin
Primary Institution: China Agricultural University
Hypothesis
The study aims to identify quantitative trait loci (QTL) for T lymphocyte subpopulations in peripheral blood in swine.
Conclusion
The study identified 27 QTL associated with T lymphocyte subpopulations, which may help in selecting for immune capacity in swine breeding.
Supporting Evidence
- The study identified 27 QTL for various T lymphocyte subpopulations.
- 11 of the identified QTL were significant at FDR < 0.05.
- The research provides insights into the genetic control of immune traits in swine.
Takeaway
Researchers looked at pig blood to find genes that help fight diseases. They found some important genes that could help make pigs healthier.
Methodology
The study involved measuring T lymphocyte subpopulations in 446 piglets from three breeds before and after vaccination, followed by genome-wide QTL mapping.
Limitations
The study may not account for environmental factors affecting immune response since all pigs were raised under the same conditions.
Participant Demographics
The sample consisted of 446 piglets from three different breed populations.
Statistical Information
P-Value
< 0.0001
Statistical Significance
FDR < 0.10
Digital Object Identifier (DOI)
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