Conversion of deoxynivalenol to 3-acetyldeoxynivalenol in barley-derived fuel ethanol co-products with yeast expressing trichothecene 3-O-acetyltransferases
2011

Reducing Deoxynivalenol in Barley Ethanol Co-Products

Sample size: 96 publication 10 minutes Evidence: moderate

Author Information

Author(s): Khatibi Piyum A, Montanti Justin, Nghiem Nhuan P, Hicks Kevin B, Berger Greg, Brooks Wynse S, Griffey Carl A, Schmale David G III

Primary Institution: Virginia Tech, Department of Plant Pathology, Physiology and Weed Science

Hypothesis

Two enzymes (FgTRI101 and FfTRI201) would reduce DON in DDGS resulting from a series of small-scale barley ethanol fermentations.

Conclusion

Using yeast expressing trichothecene 3-O-acetyltransferases can effectively convert DON to 3ADON, reducing its concentration in DDGS.

Supporting Evidence

  • DON levels were concentrated 1.6 to 8.2 times in DDGS compared with the starting ground grain.
  • FgTRI101 converted 9.2% to 55.3% of the DON to 3ADON.
  • FfTRI201 was more effective at acetylating DON than FgTRI101.

Takeaway

This study shows that special yeast can change a harmful substance in barley into a less harmful one during the process of making ethanol.

Methodology

Yeast strains were transformed with genes for trichothecene 3-O-acetyltransferases and used in small-scale ethanol fermentations of barley.

Potential Biases

Potential bias in the selection of barley cultivars and yeast strains used in the study.

Limitations

The study did not explore the long-term effects of consuming DDGS with reduced DON levels.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1754-6834-4-26

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