OBJECTIVE SLEEP QUALITY ASSOCIATES WITH PLASMA BIOMARKER FOR COGNITIVE IMPAIRMENT
2024

Sleep Quality and Cognitive Impairment Biomarker in Nurses

Sample size: 35 publication Evidence: moderate

Author Information

Author(s): Kim Jinyoung, Dangler Kevin, Nam Stephanie, Fudolig Miguel, Kinney Jefferson

Primary Institution: University of Nevada Las Vegas

Hypothesis

Objective sleep quality measures are associated with plasma levels of Eotaxin-1, an early biomarker for cognitive impairment.

Conclusion

There is a correlation between sleep quality on workdays and levels of a biomarker for cognitive impairment.

Supporting Evidence

  • WASO increased by 8% on days off compared to workdays.
  • %N3 decreased by 1% on days off.
  • Higher WASO and lower %N3 on workdays were significantly associated with increasing levels of Eotaxin-1.

Takeaway

If nurses don't sleep well during workdays, it might be linked to a chemical in their blood that shows they could have memory problems later.

Methodology

Data from 35 nurses who underwent home sleep studies and had blood samples taken were analyzed.

Potential Biases

Potential bias due to the specific demographic of participants (nurses).

Limitations

The study only included nurses and may not generalize to other populations.

Participant Demographics

Nurses from the University of Nevada Las Vegas.

Statistical Information

P-Value

p<.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/geroni/igae098.2234

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