Herpesviruses and Autophagy: Catch Me If You Can!
2010
Herpesviruses and Autophagy: Catch Me If You Can!
publication
Evidence: moderate
Author Information
Author(s): Yolaine Cavignac, Audrey Esclatine
Primary Institution: INSERM U756 and Université Paris-Sud 11
Hypothesis
Host cells try to control Herpesvirus infections by activating the autophagic machinery.
Conclusion
Herpesviruses have evolved various strategies to evade the host's autophagic response.
Supporting Evidence
- Autophagy helps eliminate intracellular pathogens.
- Herpesviruses have developed mechanisms to inhibit autophagy.
- Autophagy enhances the presentation of viral proteins to the immune system.
- Different Herpesviruses employ various strategies to evade autophagic degradation.
Takeaway
This study talks about how some viruses, like Herpesviruses, can trick our body's cleaning system, called autophagy, to avoid being destroyed.
Methodology
The review summarizes recent advances in understanding the interplay between autophagy and Herpesviruses.
Digital Object Identifier (DOI)
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