Mycobacterium sp. as a Possible Cause of Hypersensitivity Pneumonitis in Machine Workers
1999

Mycobacteria as a Cause of Hypersensitivity Pneumonitis in Metal Workers

Sample size: 6 publication Evidence: moderate

Author Information

Author(s): Brian G. Shelton, W. Dana Flanders, George K. Morris

Primary Institution: PathCon Laboratories

Hypothesis

Aerosolized mycobacteria colonizing metal removal fluids likely cause hypersensitivity pneumonitis in workers.

Conclusion

The study suggests a possible association between mycobacteria and hypersensitivity pneumonitis in metal workers exposed to contaminated fluids.

Supporting Evidence

  • High airborne concentrations of mycobacteria were documented in the workplace.
  • Six out of seven facilities with known HP had mycobacteria present.
  • Outbreaks of HP in hot tubs have been linked to mycobacteria.

Takeaway

Some workers who use special cutting fluids may get sick from tiny germs called mycobacteria that live in those fluids.

Methodology

The study involved case reports and retrospective review of samples from metal working facilities.

Limitations

The data is based on existing records and not a prospectively designed study.

Participant Demographics

The cases reported involved male workers, primarily middle-aged.

Statistical Information

P-Value

0.01

Confidence Interval

1.5-2194.47

Statistical Significance

p = 0.01

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