Cough and Asthma
2011

Cough and Asthma

Sample size: 49 publication Evidence: moderate

Author Information

Author(s): Niimi Akio

Primary Institution: Graduate School of Medicine, Kyoto University

Hypothesis

Cough variant asthma (CVA) is a common cause of chronic cough that may progress to classic asthma if untreated.

Conclusion

Inhaled corticosteroids are crucial for controlling cough in CVA and may prevent progression to classic asthma.

Supporting Evidence

  • Cough variant asthma is one of the most common causes of chronic cough.
  • 30 to 40% of adult patients with CVA may progress to classic asthma if untreated.
  • Inhaled corticosteroids improve cough and reduce the risk of progression to classic asthma.

Takeaway

Cough variant asthma is a type of asthma where coughing is the only symptom, and treating it with inhaled steroids can help prevent it from getting worse.

Methodology

A cross-sectional study was conducted to examine mucin levels in induced sputum from patients with cough variant asthma and other conditions.

Potential Biases

There is a risk of selection bias due to the nature of patient enrollment.

Limitations

The study may have selection bias as only patients who succeeded in sputum induction were included.

Participant Demographics

The study included 49 patients with classic asthma, 53 with chronic cough (39 with CVA), and 11 healthy subjects.

Statistical Information

P-Value

0.014

Statistical Significance

p=0.014

Digital Object Identifier (DOI)

10.2174/157339811794109327

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