Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia
2011

Metabolic Syndrome in Schizophrenia Patients in Japan

Sample size: 1186 publication Evidence: high

Author Information

Author(s): Sugawara Norio, Yasui-Furukori Norio, Sato Yasushi, Kishida Ikuko, Yamashita Hakuei, Saito Manabu, Furukori Hanako, Nakagami Taku, Hatakeyama Mitsunori, Kaneko Sunao

Primary Institution: Hirosaki University School of Medicine

Hypothesis

The study aims to compare the prevalence of metabolic syndrome between inpatients and outpatients with schizophrenia in Japan.

Conclusion

Outpatients with schizophrenia or schizoaffective disorder in Japan had a high prevalence of metabolic syndrome compared to inpatients.

Supporting Evidence

  • The overall metabolic syndrome prevalence was 15.8% in inpatients and 48.1% in outpatients.
  • Being a schizophrenic outpatient was a significant independent factor for developing metabolic syndrome.
  • The prevalence of metabolic syndrome was higher in all age groups for males and in females over 40 years of age.

Takeaway

People with schizophrenia who live outside the hospital are more likely to have health problems related to their metabolism than those who stay in the hospital.

Methodology

The study recruited 759 inpatients and 427 outpatients diagnosed with schizophrenia or schizoaffective disorder from 7 psychiatric hospitals using a cross-sectional design.

Potential Biases

Potential bias due to the exclusion of unmedicated patients and those with pre-existing metabolic disturbances.

Limitations

The study was cross-sectional, limited to specific hospitals, and did not include other population groups or certain parameters that may contribute to metabolic syndrome.

Participant Demographics

759 inpatients (355 males, 404 females) and 427 outpatients (215 males, 212 females) diagnosed with schizophrenia or schizoaffective disorder.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI = 4.83 to 11.86 for males, 95% CI = 2.70 to 6.67 for females

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1744-859X-10-21

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