Effect of lifestyle intervention for people with diabetes or prediabetes in real-world primary care: propensity score analysis
2011

Effect of Lifestyle Intervention for Diabetes in Primary Care

Sample size: 2818 publication Evidence: low

Author Information

Author(s): Linmans Joris J, Spigt Mark G, Deneer Linda, Lucas Annelies EM, de Bakker Marlies, Gidding Luc G, Linssen Rik, Knottnerus J André

Primary Institution: Maastricht University

Hypothesis

Can a lifestyle intervention improve health outcomes for patients with prediabetes or type 2 diabetes in a real-world primary care setting?

Conclusion

The lifestyle program had small effects that were not statistically significant.

Supporting Evidence

  • The intervention group showed a small reduction in HbA1c and fasting glucose, but it was not statistically significant.
  • Patients in the intervention group were younger and had fewer cardiovascular diseases compared to the control group.
  • Despite the lifestyle program's implementation, the effects were not clinically relevant.

Takeaway

This study looked at a program to help people with diabetes eat better and exercise more, but it didn't really help them get better.

Methodology

Retrospective comparative medical records analysis using propensity score matching.

Potential Biases

Potential bias due to unblinded healthcare providers and patients.

Limitations

The study could not control for unmeasured confounding and treatment adherence was not tracked after the first consultation.

Participant Demographics

Patients with prediabetes or type 2 diabetes from ten primary healthcare centres in the Netherlands.

Statistical Information

P-Value

P = 0.07 for HbA1c and P = 0.08 for fasting glucose.

Confidence Interval

CI = -0.30 to 0.06 for HbA1c and CI = -0.38 to 0.04 for fasting glucose.

Digital Object Identifier (DOI)

10.1186/1471-2296-12-95

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