Cortical Evoked Potentials in Children of Diabetic Mothers
Author Information
Author(s): Mario Brinciotti, Angela Napoli, Antonio Mittica, Olimpia Bitterman, Maria Matricardi
Primary Institution: Sapienza University of Rome
Hypothesis
Do the visual and somatosensory evoked potentials in children of type 1 diabetic mothers show delays compared to controls?
Conclusion
Children of type 1 diabetic mothers showed significant delays in cortical evoked responses to visual and somatosensory stimulation compared to controls.
Supporting Evidence
- Children of diabetic mothers showed delayed mean latency of visual and somatosensory evoked potentials.
- Pathological responses were found in 19% of the children studied.
- The delay in evoked responses was still present at the age of three years.
Takeaway
Kids whose moms had diabetes while pregnant take longer to respond to visual and touch tests than kids whose moms didn't have diabetes.
Methodology
The study recorded visual and somatosensory evoked potentials in 16 children of type 1 diabetic mothers and compared them to 23 controls.
Potential Biases
Potential bias due to lack of knowledge of mothers' metabolic status during recordings.
Limitations
The study had a 33% attrition rate from the initial sample of infants.
Participant Demographics
16 children (11 females, 5 males) aged 3 years, offspring of type 1 diabetic mothers.
Statistical Information
P-Value
<0.001
Confidence Interval
99%
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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