Antioxidant, Antimicrobial and Antiproliferative Activities of Five Lichen Species
Author Information
Author(s): Mitrović Tatjana, Stamenković Slaviša, Cvetković Vladimir, Tošić Svetlana, Stanković Milan, Radojević Ivana, Stefanović Olgica, Čomić Ljiljana, Đačić Dragana, Ćurčić Milena, Marković Snežana
Primary Institution: Department of Biology and Ecology, Faculty of Science and Mathematics, University of Niš
Hypothesis
The study aims to evaluate the antioxidant, antimicrobial, and antiproliferative capacities of five lichen species.
Conclusion
The lichen species Hypogymnia physodes and Cladonia foliacea demonstrated the best antioxidant, antimicrobial, and antiproliferative activities.
Supporting Evidence
- Hypogymnia physodes showed the strongest DPPH radical scavenging effect.
- All lichen species showed the ability to induce apoptosis of HCT-116 cells.
- The highest antimicrobial activity among lichens was demonstrated by Hypogymnia physodes and Cladonia foliacea.
- Extracts of Flavoparmelia caperata, Hypogymnia physodes, and Cladonia foliacea demonstrated significant inhibition of cell growth.
Takeaway
This study looked at how certain lichens can help fight germs and cancer, and found that some lichens are really good at it.
Methodology
The study used methanol extracts of five lichen species and evaluated their antioxidant, antimicrobial, and antiproliferative activities through various assays.
Limitations
The study did not isolate and identify the active compounds responsible for the observed activities.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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