Oxidative Balance Score and Diabetic Kidney Disease Risk
Author Information
Author(s): Liang Yu, Xu Zhonggao, Wang Wanning
Primary Institution: The First Hospital of Jilin University, Changchun, Jilin, China
Hypothesis
This study aimed to evaluate the relationship between oxidative balance score (OBS) and the risk of diabetic kidney disease (DKD) in individuals with Type 2 diabetes mellitus (T2DM).
Conclusion
OBS negatively correlates with the risk of DKD among individuals with T2DM.
Supporting Evidence
- Participants in the highest quartile of OBS had a 50% lower risk of DKD compared to those in the lowest quartile.
- The study evaluated 3,669 T2DM participants, among whom DKD prevalence was 30.87%.
- High OBS is associated with better glycemic control and reduced risk of diabetes.
- Subgroup analysis showed that the relationship between OBS and DKD was consistent across various demographics.
Takeaway
Eating foods that help balance antioxidants and harmful substances can lower the risk of kidney problems in people with diabetes.
Methodology
A cross-sectional study was conducted using multiple logistic regression on NHANES data.
Potential Biases
Unknown or unmeasured confounders could affect the results.
Limitations
The study design was cross-sectional, limiting causal inference, and potential confounding factors may not have been fully accounted for.
Participant Demographics
The study included 3,669 participants, with 56.69% male and a majority being non-Hispanic white.
Statistical Information
P-Value
0.50
Confidence Interval
95% CI: 0.39 to 0.65
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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