Roles of Streptococcus mutans in human health: beyond dental caries
2024

Roles of Streptococcus mutans in human health: beyond dental caries

publication Evidence: moderate

Author Information

Author(s): Fang Yanke, Chen Xin, Chu Chun Hung, Yu Ollie Yiru, He Jinzhi, Li Mingyun

Primary Institution: State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, China

Hypothesis

The traits of Streptococcus mutans contribute to systemic diseases beyond dental caries.

Conclusion

Streptococcus mutans can cause systemic diseases by evading the immune system and triggering inflammatory responses.

Supporting Evidence

  • Streptococcus mutans can enter the bloodstream and adhere to various tissues, leading to systemic diseases.
  • It can trigger inflammatory reactions that may damage organs.
  • Clinical studies have linked S. mutans to cardiovascular diseases and other systemic conditions.

Takeaway

Streptococcus mutans, a bacteria usually linked to cavities, can also make people sick in other parts of the body.

Methodology

This review analyzes existing studies on the pathogenic mechanisms of Streptococcus mutans in systemic diseases.

Limitations

The review is based on correlative findings and lacks comprehensive evaluations of S. mutans' impact on systemic diseases.

Digital Object Identifier (DOI)

10.3389/fmicb.2024.1503657

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