The Uptake and Accuracy of Oral Kits for HIV Self-Testing in High HIV Prevalence Setting: A Cross-Sectional Feasibility Study in Blantyre, Malawi
2011

HIV Self-Testing in Malawi

Sample size: 298 publication 10 minutes Evidence: high

Author Information

Author(s): Choko Augustine Talumba, Desmond Nicola, Webb Emily L., Chavula Kondwani, Napierala-Mavedzenge Sue, Gaydos Charlotte A., Makombe Simon D., Chunda Treza, Squire S. Bertel, French Neil, Mwapasa Victor, Corbett Elizabeth L.

Primary Institution: Malawi-Liverpool Wellcome Trust Clinical Research Programme

Hypothesis

Can supervised oral HIV self-testing yield accurate results in a high-prevalence setting?

Conclusion

Oral supervised self-testing was highly acceptable and accurate, indicating strong community readiness to adopt this method.

Supporting Evidence

  • 99.2% accuracy in self-testing results.
  • 94.5% acceptability of self-test kits from neighbors.
  • 10% of participants required additional help during testing.
  • 18.5% HIV prevalence among participants.

Takeaway

People in Malawi found it easy and liked testing for HIV at home using a simple kit, which could help more people know their HIV status.

Methodology

Participants were randomly selected from households and community peer groups, offered self-testing with confirmatory testing, and data were collected through interviews and questionnaires.

Potential Biases

Potential bias due to the high participation rate of individuals who may have been more willing to test.

Limitations

The study did not investigate linkage into care following a positive HIV test.

Participant Demographics

283 participants, 48% men, median age 27 years, with a significant portion reporting food shortages.

Statistical Information

P-Value

0.001

Confidence Interval

95% CI 97.0–100.0%

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1371/journal.pmed.1001102

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