Motivated Proteins: A web application for studying small three-dimensional protein motifs
2009

Motivated Proteins: A web application for studying small three-dimensional protein motifs

Sample size: 417 publication Evidence: moderate

Author Information

Author(s): David P Leader, E James Milner-White

Primary Institution: University of Glasgow

Conclusion

Motivated Proteins is a publicly and freely accessible web application that enables protein scientists to study small three-dimensional motifs without requiring knowledge of either Structured Query Language or the underlying database schema.

Supporting Evidence

  • The application allows for specific queries related to protein motifs.
  • It provides visualizations of motifs in the context of protein structures.
  • The database includes over 400 representative proteins.

Takeaway

Motivated Proteins is a tool that helps scientists look at tiny shapes in proteins, making it easier to understand how proteins work without needing to know complicated coding.

Methodology

A relational database was constructed to store protein motifs, and a web application was built to allow users to query and visualize these motifs.

Limitations

The database may not include all proteins, which could limit the queries available to users.

Digital Object Identifier (DOI)

10.1186/1471-2105-10-60

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