Long-Term Effects of Chikungunya Virus on Joint Health
Author Information
Author(s): Sissoko Daouda, Malvy Denis, Ezzedine Khaled, Renault Philippe, Moscetti Frederic, Ledrans Martine, Pierre Vincent
Primary Institution: Institut de Veille Sanitaire, La Réunion, France
Hypothesis
What are the long-term rheumatic outcomes of Chikungunya virus infection?
Conclusion
The study found that 57% of participants experienced persistent rheumatic symptoms 15 months after Chikungunya virus infection.
Supporting Evidence
- 84 out of 147 participants reported rheumatic symptoms at 15 months.
- 63% of those with symptoms reported permanent trouble.
- Age ≥45 years was a significant predictor of nonrecovery.
Takeaway
Many people who get sick from the Chikungunya virus can still have joint pain and problems long after they feel better.
Methodology
A retrospective cohort study was conducted with participants interviewed by telephone about their health 15 months after infection.
Potential Biases
Self-reported data may lead to recall bias regarding symptoms.
Limitations
The study may not be generalizable due to the exclusion of individuals without phone contact and those under 16 years old.
Participant Demographics
The study included 69% women and 31% men, with a mean age of 52 years.
Statistical Information
P-Value
0.002
Confidence Interval
95% CI 1.7–9.7
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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