Phosphaturic mesenchymal tumor of the popliteal fossa: a case report and literature review
2024

Case Report on a Rare Tumor Causing Bone Weakness

Sample size: 1 publication Evidence: moderate

Author Information

Author(s): Wang Yingjie, Liu Shiwei, Li Caixia, Song Wenjing, Zhang Yimin, Wang Jun

Primary Institution: Weifang People’s Hospital, Shandong Second Medical University, Weifang, Shandong, China

Hypothesis

Can a phosphaturic mesenchymal tumor in the popliteal fossa cause tumor-induced osteomalacia?

Conclusion

Surgical removal of the tumor led to normalization of blood phosphorus levels and significant symptom relief.

Supporting Evidence

  • The patient had persistent pain and was misdiagnosed with osteoporosis and osteoarthritis.
  • Imaging revealed a cystic and solid mass in the popliteal fossa.
  • Post-surgery, the patient's blood phosphorus levels returned to normal within a week.

Takeaway

A man had a rare tumor that made his bones weak, but after doctors took it out, he felt much better and his blood tests improved.

Methodology

The patient underwent imaging studies, laboratory tests, and surgical excision of the tumor, followed by pathological examination.

Limitations

The rarity of the condition may limit generalizability and awareness among clinicians.

Participant Demographics

A 42-year-old man with no prior medical history.

Digital Object Identifier (DOI)

10.3389/fonc.2024.1501499

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