Understanding HIV's Impact on Maternal Mortality
Author Information
Author(s): James E. Rosen, Isabelle de Zoysa, Karl Dehne, Viviana Mangiaterra, Quarraisha Abdool-Karim
Hypothesis
How do different methods for estimating HIV-associated maternal mortality affect global and regional estimates?
Conclusion
HIV significantly contributes to maternal mortality, particularly in high-prevalence regions like sub-Saharan Africa.
Supporting Evidence
- HIV is a leading cause of maternal death in high-prevalence countries.
- Estimates of HIV-associated maternal deaths vary significantly between different models.
- The majority of HIV-associated maternal deaths occur in sub-Saharan Africa.
Takeaway
HIV makes it harder for pregnant women to stay healthy, and many women die because of it, especially in places where HIV is common.
Methodology
The study reviews and compares different statistical models used to estimate HIV-associated maternal deaths.
Potential Biases
Different models may produce varying estimates due to assumptions about the relationship between HIV and maternal mortality.
Limitations
Estimates are based on incomplete data and face challenges in accurately identifying causes of maternal deaths.
Participant Demographics
Focuses on women of reproductive age, particularly in high-HIV-burden countries.
Statistical Information
Confidence Interval
uncertainty interval 15,341–29,120 for HIV-associated maternal deaths
Digital Object Identifier (DOI)
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