Relationships between anaemia and parasitic infections in Kenyan schoolchildren: A Bayesian hierarchical modelling approach
2008

Anaemia and Parasitic Infections in Kenyan Schoolchildren

Sample size: 1523 publication 10 minutes Evidence: moderate

Author Information

Author(s): Artemis Koukounari, Benson Estambale, Kiambo Njagi, Bonnie Cundill, Anthony Ajanga, Christopher Crudder, Julius Otido, Matthew C.H. Jukes, Siân E. Clarke, Simon Brooker

Primary Institution: Imperial College London

Hypothesis

What is the relationship between anaemia and different parasitic infections in schoolchildren?

Conclusion

Malaria and heavy Schistosoma mansoni infections significantly contribute to lower haemoglobin levels and increased anaemia among schoolchildren.

Supporting Evidence

  • Children infected with Plasmodium falciparum had lower haemoglobin concentrations.
  • Heavy Schistosoma mansoni infection was linked to higher rates of anaemia.
  • Stunted children had lower mean haemoglobin levels compared to non-stunted children.

Takeaway

This study found that kids with certain infections, like malaria and schistosomiasis, have lower blood levels, which can make them feel tired and sick.

Methodology

Cross-sectional study using Bayesian hierarchical modelling to analyze haemoglobin levels and parasitic infections.

Potential Biases

Potential biases due to reliance on self-reported data and the accuracy of age reporting.

Limitations

The cross-sectional design limits causal interpretations and may not capture all relevant factors affecting anaemia.

Participant Demographics

Children aged 10-21 years from 30 primary schools in western Kenya.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 12.28–12.76

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1016/j.ijpara.2008.05.013

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