New Orientia tsutsugamushi Strain from Scrub Typhus in Australia
1998

New Strain of Scrub Typhus Identified in Australia

Sample size: 1 publication Evidence: low

Author Information

Author(s): Dimitri M. Odorico, Stephen R. Graves, Bart Currie, Julian Catmull, Zoltan Nack, Sharon Ellis, Ling Wang, David J. Miller

Primary Institution: James Cook University

Hypothesis

The study aims to identify and characterize a new strain of Orientia tsutsugamushi responsible for scrub typhus in Australia.

Conclusion

A new strain of scrub typhus, designated Litchfield, was identified from a patient in Northern Territory, differing significantly from known strains.

Supporting Evidence

  • The new strain was isolated from a patient with scrub typhus.
  • Serologic tests confirmed the diagnosis of scrub typhus.
  • The strain showed significant genetic differences from known strains.
  • Previous isolates of O. tsutsugamushi have been made from Queensland.

Takeaway

Doctors found a new type of germ that causes scrub typhus in Australia, which is different from the ones they knew before.

Methodology

The study involved serologic tests, mouse inoculation, PCR for DNA detection, and 16S rDNA sequencing.

Limitations

The study is based on a single case, limiting broader conclusions about the strain's prevalence.

Participant Demographics

The patient was a 38-year-old male construction worker.

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