Evaluation of an automated haemolytic method for the determination of ASO antibodies
1985
Evaluation of an automated hemolytic method for the determination of ASO antibodies
Sample size: 600
publication
Evidence: high
Author Information
Author(s): F. Parri, E. de Majo
Hypothesis
Can the new Taso-tec/Taso-matic automatic system accurately determine ASO titers?
Conclusion
The automatic method shows excellent correlation with the reference method for determining ASO antibodies.
Supporting Evidence
- The method is based on the property that erythrocytes are not hemolyzed when Streptolysin O is oxidized.
- The addition of a reducing agent allows the initial rate of hemolysis to be followed.
- The rate of hemolysis is proportional to the ASO titer of the sample.
- The automatic system can perform up to 17 serum kinetic determinations simultaneously in 30 minutes.
- The results show excellent correlation between the automatic method and the reference method.
Takeaway
This study tested a new machine that can quickly check for a specific antibody in blood samples, and it works really well.
Methodology
The study involved using the Taso-tec/Taso-matic system to automatically determine ASO titers in serum samples.
Want to read the original?
Access the complete publication on the publisher's website