Adrenal Suppression: A Guide for Screening and Management
Author Information
Author(s): Ahmet Alexandra, Kim Harold, Spier Sheldon
Primary Institution: University of Ottawa, Children's Hospital of Eastern Ontario
Hypothesis
What are the risks and management strategies for adrenal suppression in children using inhaled corticosteroids?
Conclusion
Adrenal suppression is a serious but often unrecognized complication of high-dose inhaled corticosteroid therapy in children, which can lead to significant health issues if not properly managed.
Supporting Evidence
- Adrenal suppression can persist for up to 1 year after stopping corticosteroid treatment.
- More than 60 cases of adrenal suppression have been documented in children treated with high doses of fluticasone.
- Regular follow-up and awareness can minimize the risk of adrenal suppression.
Takeaway
Inhaled corticosteroids can sometimes make it hard for the body to produce a hormone called cortisol, which is important for stress. Doctors need to check for this problem, especially in kids taking high doses.
Methodology
This review summarizes current literature and provides recommendations for screening and managing adrenal suppression in children using inhaled corticosteroids.
Potential Biases
Potential bias may arise from the authors' affiliations and funding sources.
Limitations
The review highlights the lack of national guidelines for screening and the variability in practices among healthcare centers.
Participant Demographics
The article primarily discusses children and adolescents with asthma.
Digital Object Identifier (DOI)
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