Efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 Ctenocephalides felis flea strain infesting cats
2011

Effectiveness of Flea Treatments for Cats

Sample size: 90 publication 10 minutes Evidence: high

Author Information

Author(s): Michael W Dryden, Patricia A Payne, Vicki Smith, Joe Hostetler

Primary Institution: Kansas State University

Hypothesis

The study aims to evaluate and compare the efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 flea strain infesting cats.

Conclusion

The imidacloprid + moxidectin formulation was found to be more effective than selamectin in killing fleas on cats.

Supporting Evidence

  • Imidacloprid + moxidectin provided 99.8% efficacy at 24 hours post-treatment.
  • Selamectin's efficacy dropped to 87.1% by day 28.
  • Both treatments showed high efficacy at 48 hours post-treatment.
  • Imidacloprid + moxidectin achieved 100% efficacy within 12 hours post-treatment.

Takeaway

This study tested two flea treatments for cats and found that one treatment worked much better than the other at getting rid of fleas quickly.

Methodology

Two studies were conducted with purpose-bred cats to compare the efficacy of two flea treatments at various time points after application.

Potential Biases

Potential bias due to funding from manufacturers of the treatments being tested.

Limitations

The studies were conducted on a specific flea strain and may not be generalizable to all flea populations.

Participant Demographics

Cats were purpose-bred Domestic Short Hair, aged between 7 and 12 months, with equal gender distribution.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1756-3305-4-174

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