Effect of Transcranial Magnetic Stimulation (TMS) on Parietal and Premotor Cortex during Planning of Reaching Movements
2009

Effect of TMS on Brain Areas During Movement Planning

Sample size: 76 publication 10 minutes Evidence: moderate

Author Information

Author(s): Busan Pierpaolo, Barbera Claudia, Semenic Mauro, Monti Fabrizio, Pizzolato Gilberto, Pelamatti Giovanna, Battaglini Piero Paolo

Primary Institution: University of Trieste, Trieste, Italy

Hypothesis

Can transcranial magnetic stimulation (TMS) affect the planning of reaching movements in the parietal and premotor cortex?

Conclusion

TMS can facilitate the planning of reaching movements by affecting cortical dynamics in the parieto-frontal network.

Supporting Evidence

  • TMS applied at 75% of mean reaction time significantly shortened reaction times.
  • Facilitatory effects of TMS were observed in both the parietal and premotor cortex.
  • Participants showed variability in reaction times based on skill improvement.
  • Statistical analysis revealed significant interactions between TMS and stimulation point.

Takeaway

This study shows that using a special technique called TMS on certain parts of the brain can help people plan their reaching movements better.

Methodology

The study used TMS to stimulate the parietal and premotor cortex while participants planned reaching movements, measuring reaction times.

Potential Biases

Potential bias due to the small sample size in some experiments and the specific demographic of participants.

Limitations

The study may not generalize to all populations as it only included right-handed individuals.

Participant Demographics

76 healthy right-handed volunteers, aged 19-56, with a mean age of 27.1.

Statistical Information

P-Value

p=0.0066

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0004621

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