A computerized automatic apparatus for determination of mercury in biological samples
1984

Automatic Mercury Analysis in Biological Samples

Sample size: 16 publication Evidence: moderate

Author Information

Author(s): Osten Einarsson, G6sta Lindstedt, Torgil Bergström

Primary Institution: National Board of Occupational Safety and Health, Chemistry Division

Hypothesis

The new computerized apparatus can improve the determination of mercury in biological samples.

Conclusion

The automated apparatus provides a rapid and sensitive method for analyzing mercury in urine and blood samples.

Supporting Evidence

  • The apparatus can analyze 60 samples in about 2 hours without supervision.
  • The detection limit was about 0.25 ng of mercury per sample.
  • Variations in sensitivity due to matrix influences are within 10%, which is acceptable for routine control.
  • Different methods of evaluation showed that peak area is a safer method than peak height.

Takeaway

This study shows a new machine that can quickly check for mercury in pee and blood, helping keep people safe from pollution.

Methodology

The study involved using a computerized apparatus to analyze urine and blood samples for mercury content using atomic absorption spectrophotometry.

Potential Biases

Potential bias due to variations in sample matrix affecting sensitivity.

Limitations

The study did not test alternative reducing agents that could improve the method.

Participant Demographics

Samples included urine and blood from occupationally unexposed persons.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

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