Inflammatory Markers of Aging in Older Adults with Schizophrenia
Author Information
Author(s): Leutwyler Heather, Chui M K, Schneider Kevin, LaHue Sara, Furman David, Newman John
Primary Institution: University of California San Francisco, Buck Institute for Research on Aging
Hypothesis
The study investigates the relationships between health and inflammaging biomarkers in older adults with schizophrenia.
Conclusion
Specific inflammatory cytokines are linked to worse cognitive and physical health in older adults with schizophrenia.
Supporting Evidence
- Inflammaging is linked to earlier onset of aging-related diseases in schizophrenia.
- Specific inflammatory cytokines were associated with worse cognition and physical health.
- No significant associations were found with SASP composite scores.
Takeaway
Older adults with schizophrenia may have inflammation that affects their health, and certain inflammatory markers can indicate how well they think and function.
Methodology
Cross-sectional analysis of plasma from older adults with schizophrenia, assessing neurocognition and physical health.
Limitations
The study is limited by its small sample size and cross-sectional design.
Participant Demographics
Mean age of participants was 59.5 years.
Digital Object Identifier (DOI)
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