A diagnostic dilemma: a case report
2009
A Case Report on Wegener's Granulomatosis Diagnosis
Sample size: 1
publication
Evidence: low
Author Information
Author(s): David M Comer, J David Edgar
Primary Institution: Belfast City Hospital and Royal Victoria Hospital, Belfast, UK
Conclusion
ANCA testing was crucial for the early diagnosis of Wegener's Granulomatosis in this patient.
Supporting Evidence
- The patient presented with acute bilateral foot drop and paraesthesia.
- ANCA testing revealed positive results, leading to a diagnosis of Wegener's Granulomatosis.
- The patient showed a significant decrease in serum C reactive protein after steroid treatment.
Takeaway
A 79-year-old woman had foot problems that turned out to be a rare disease called Wegener's Granulomatosis, and special blood tests helped doctors figure it out.
Methodology
The case involved clinical examination, laboratory tests, imaging studies, and ANCA testing.
Potential Biases
Potential for bias in diagnosis due to atypical presentation and reliance on ANCA testing.
Limitations
The case report is based on a single patient, which limits generalizability.
Participant Demographics
79-year-old Caucasian female.
Digital Object Identifier (DOI)
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