Obtaining consent for future research with induced pluripotent cells: Opportunities and challenges
2009

Consent for Future Research with Induced Pluripotent Cells

publication Evidence: moderate

Author Information

Author(s): Katriina Aalto-Setälä, Bruce R. Conklin, Bernard Lo

Primary Institution: Gladstone Institute of Cardiovascular Disease

Hypothesis

How can the consent process for donating somatic cells for iPS cell derivation be designed to facilitate future research?

Conclusion

The study emphasizes the importance of obtaining informed consent for future research involving induced pluripotent stem cells to respect donor autonomy and promote public trust.

Supporting Evidence

  • iPS cells provide opportunities to study diseases and develop therapies.
  • Ethical concerns about consent for future research are particularly relevant for iPS cells.
  • Public support for consent processes varies, with many willing to donate if asked.

Takeaway

Scientists need to ask people for permission to use their cells for future research, so everyone knows what will happen with their cells.

Methodology

The paper discusses ethical guidelines and consent processes for using somatic cells to derive iPS cells.

Potential Biases

Potential bias in public opinion regarding consent for sensitive research uses of iPS cells.

Limitations

The paper does not provide empirical data or specific case studies to support its recommendations.

Digital Object Identifier (DOI)

10.1371/journal.pbio.1000042

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