Historical Perspectives in the Development of Antiviral Agents Against Poxviruses
2010
Historical Perspectives in the Development of Antiviral Agents Against Poxviruses
publication
Evidence: moderate
Author Information
Author(s): De Clercq Erik
Primary Institution: Rega Institute for Medical Research, Department of Microbiology and Immunology, Leuven, Belgium
Conclusion
The study reviews the historical development of antiviral agents against poxviruses, highlighting the efficacy of various compounds over the years.
Supporting Evidence
- The first antiviral agents discovered were thiosemicarbazones, effective against vaccinia virus.
- Numerous candidate compounds for treating poxvirus infections have been identified over the past 50 years.
- Interferon and its inducers have shown efficacy in antiviral treatments against poxviruses.
Takeaway
This study looks at how scientists have developed medicines to fight poxviruses over the years, showing that many different drugs have been tried.
Methodology
The article reviews historical data and findings related to antiviral agents against poxviruses.
Limitations
The study primarily focuses on historical data and may not include the latest developments in antiviral research.
Digital Object Identifier (DOI)
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