Prognostic Factors in Lung Metastasis from Nasopharyngeal Carcinoma
Author Information
Author(s): Cao Xun, Luo Rong-Zhen, He Li-Ru, Li Yong, Lin Wen-Qian, Chen You-Fang, Wen Zhe-Sheng
Primary Institution: Sun Yat-Sen University Cancer Center
Hypothesis
The study aims to identify prognostic factors and establish risk grouping in patients with lung metastases from nasopharyngeal carcinoma.
Conclusion
Clinical variables can provide important prognostic indicators for survival in patients with lung metastases from nasopharyngeal carcinoma.
Supporting Evidence
- The median overall survival was 51.5 months.
- Age, T classification, N classification, and disease-free interval were significant predictors of survival.
- Patients were classified into low, intermediate, and high-risk subsets based on prognostic factors.
Takeaway
Doctors can use certain factors to predict how long patients with lung cancer from nasopharyngeal carcinoma might live, helping them plan better treatments.
Methodology
The study analyzed clinical variables of 198 patients using Cox proportional hazards regression models and Kaplan-Meier survival analysis.
Potential Biases
Potential biases may arise from the retrospective nature of the study and the non-standardized follow-up procedures.
Limitations
The study is retrospective and may have missed micrometastases due to non-standardized follow-up imaging.
Participant Demographics
{"gender":{"male":156,"female":42},"age":{"median":44.5,"range":"20-80"}}
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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