Effects of prolonged oxytetracycline supplementation on freshwater stinging catfish (Heteropneustes fossilis): a multi-biomarker approach
2024

Effects of Oxytetracycline on Freshwater Stinging Catfish

Sample size: 300 publication 10 minutes Evidence: moderate

Author Information

Author(s): Choudhary Pushpa, Naik Saisweta P., Sahoo Sameer Ranjan, Das Rakesh, Sahoo Satya Narayan, Panda Satyen Kumar, Abraham Thangapalam Jawahar, Patil Prasanna Kumar, Swain Priyabrat, Mishra Sudhansu Sekhar

Primary Institution: Indian Council of Agriculture Research (ICAR)-Central Institute of Freshwater Aquaculture (CIFA)

Hypothesis

This study sought to investigate the impacts of extended oxytetracycline supplementation on the freshwater stinging catfish Heteropneustes fossilis through a multi-biomarker approach.

Conclusion

The therapeutic dose of 80 mg/kg biomass/day was safe and tolerated well by H. fossilis, and may be used for sustainable catfish farming practices.

Supporting Evidence

  • OTC was effective against common fish pathogens.
  • Significant histological alterations were noted in the liver tissues of higher OTC dose groups.
  • OTC supplementation retarded the growth of fish.
  • Serum albumin levels increased in the therapeutic dose group.
  • Oxidative stress markers increased with higher doses of OTC.

Takeaway

The study tested how a medicine called oxytetracycline affects a type of fish. It found that a small amount is safe, but too much can hurt the fish's health.

Methodology

The study involved administering varying doses of oxytetracycline to 300 stinging catfish over 30 days and measuring various health parameters.

Limitations

The study primarily focused on one species of fish and may not be generalizable to other species or environments.

Participant Demographics

The study involved freshwater stinging catfish (Heteropneustes fossilis) sourced from local farmers.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fimmu.2024.1478114

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