The Worker Honeybee Fat Body Proteome Is Extensively Remodeled Preceding a Major Life-History Transition
2011

Honeybee Fat Body Proteome Changes Before Foraging

Sample size: 20 publication 10 minutes Evidence: high

Author Information

Author(s): Chan Queenie W. T., Mutti Navdeep S., Foster Leonard J., Kocher Sarah D., Amdam Gro V., Wolschin Florian

Primary Institution: University of British Columbia

Hypothesis

The abundance of proteins involved in lipid synthesis should change in an age-dependent manner independent of genotype.

Conclusion

The study reveals that the proteome of honeybee abdominal tissue is extensively remodeled before the transition to foraging, with significant changes in lipid metabolism.

Supporting Evidence

  • Changes in lipid metabolism are linked to the transition from in-nest tasks to foraging.
  • Proteomic analysis revealed significant differences in protein abundance between genotypes.
  • Downregulation of the insulin receptor substrate gene influenced foraging behavior.
  • Age-dependent changes in protein levels were observed in honeybee workers.
  • Findings suggest a coordinated change in carbohydrate and lipid metabolism during maturation.

Takeaway

Honeybees change their body chemistry as they grow up and get ready to go out and find food, which helps them do their jobs better.

Methodology

Proteomics approach combined with RNA interference to study protein dynamics in honeybee abdominal tissue.

Limitations

The study primarily focuses on protein changes and may not fully capture all metabolic processes involved.

Participant Demographics

Honeybee workers of two genotypes differing in foraging onset age.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0024794

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