Atypical evening cortisol profile induces visual recognition memory deficit in healthy human subjects
2008

Evening Cortisol Levels and Memory Deficits

Sample size: 44 publication Evidence: moderate

Author Information

Author(s): H. Gilpin, D. Whitcomb, K. Cho

Primary Institution: University of Sheffield

Hypothesis

Does an atypical evening cortisol profile affect visual recognition memory in healthy individuals?

Conclusion

Atypical evening salivary cortisol levels are linked to early deterioration of recognition memory.

Supporting Evidence

  • High evening cortisol levels correlate with poorer performance in visual recognition memory tasks.
  • Subjects with high evening cortisol showed significant differences in memory tasks compared to those with low evening cortisol.
  • Evening cortisol levels may disrupt sleep, which is important for memory function.

Takeaway

If your body makes too much cortisol in the evening, it can make it hard to remember things you just saw.

Methodology

Salivary cortisol levels were measured at three times during the day, and cognitive tasks were performed to assess memory.

Potential Biases

Potential bias due to self-selection of participants who volunteered for the study.

Limitations

The study only included healthy female subjects, which may limit the generalizability of the findings.

Participant Demographics

Healthy women aged 22 to 66 years, mean age 40 years.

Statistical Information

P-Value

p<0.005

Statistical Significance

p<0.005

Digital Object Identifier (DOI)

10.1186/1756-6606-1-4

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