Dynamics of infection and competition between two strains of Trypanosoma brucei brucei in the tsetse fly observed using fluorescent markers
2007

Studying Co-Infection of Trypanosoma brucei Strains in Tsetse Flies

Sample size: 1734 publication Evidence: high

Author Information

Author(s): Lori Peacock, Vanessa Ferris, Mick Bailey, Wendy Gibson

Primary Institution: University of Bristol

Hypothesis

Does intraspecific competition occur among different strains of Trypanosoma brucei in tsetse flies?

Conclusion

There is a significantly higher proportion of mixed infections than expected in tsetse flies, indicating that the two trypanosome strains do not compete but co-infect.

Supporting Evidence

  • 96.4% of infected midguts contained both red and green trypanosome strains.
  • Salivary glands with mixed infections had a higher density of trypanosomes than those with a single strain.
  • Co-infection rates were similar to those found in single strain infections.

Takeaway

The study found that two types of trypanosomes can live together in tsetse flies without fighting each other, which helps them share genes.

Methodology

Flies were infected with two strains of trypanosomes and their infections were analyzed using fluorescent markers.

Participant Demographics

Experimental tsetse flies from a laboratory colony originally from Zimbabwe.

Statistical Information

P-Value

p ≤ 0.001

Statistical Significance

p ≤ 0.001

Digital Object Identifier (DOI)

10.1186/1475-9292-6-4

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