Folic acid deficiency optic neuropathy: A case report
2008

Folic Acid Deficiency and Vision Loss

Sample size: 1 publication Evidence: low

Author Information

Author(s): de Silva Punyanganie, Jayamanne Gerard, Bolton Robin

Primary Institution: Doncaster Royal Infirmary, UK

Hypothesis

Can folic acid deficiency lead to optic neuropathy without other clinical signs of deficiency?

Conclusion

Folic acid deficiency can present as visual abnormalities and can be corrected with vitamin supplementation.

Supporting Evidence

  • Investigations revealed severe folate deficiency with normal vitamin B12 levels.
  • Correction of folate levels with oral supplementation led to improvement in visual acuity.
  • The patient had a history of low folate levels three years prior.

Takeaway

A woman lost her vision because she didn't have enough folic acid, but after taking vitamins, her sight got better.

Methodology

Case report detailing the patient's history, clinical examination, and treatment.

Limitations

Only one case is reported, limiting generalizability.

Participant Demographics

44-year-old woman with a history of moderate alcohol and tobacco use.

Digital Object Identifier (DOI)

10.1186/1752-1947-2-299

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