Validity and Responsiveness of Health Status Measures in Schizophrenia
Author Information
Author(s): Diana Papaioannou, John Brazier, Glenys Parry
Primary Institution: University of Sheffield
Hypothesis
This review aims to assess the construct validity and responsiveness of four generic health status measures in schizophrenia.
Conclusion
The evidence base is limited, raising doubts about the use of generic health measures like EQ-5D and SF-36 in patients with schizophrenia.
Supporting Evidence
- Thirty-three studies were identified that provided data on the validity and/or responsiveness of the instruments.
- Most evidence concerns the SF-36 and EQ-5D, showing known group validity.
- The evidence for convergent validity and responsiveness was mixed, with contradictory results.
Takeaway
This study looked at how well certain health surveys work for people with schizophrenia, and found that they might not be the best fit.
Methodology
A systematic review of the literature was conducted, searching ten databases and appraising studies for validity and responsiveness of health status measures.
Potential Biases
Potential selection bias due to incomplete reporting of missing HRQL data.
Limitations
The evidence base is limited in important respects, including issues with the measures used in validation studies.
Participant Demographics
Participants included both genders, with ages ranging from 20.3 to 57.9 years.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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